Professional
Technical
IVT
CAH newborn screening
Routine blood test performed on newborns to detect congenital adrenal hyperplasia by measuring 17-hydroxyprogesterone levels.
Full Definition
A mandatory screening test performed within the first few days of life to identify infants with congenital adrenal hyperplasia (CAH). The test measures elevated 17-hydroxyprogesterone levels in blood spots collected on filter paper. Early detection is crucial as CAH can cause life-threatening salt-wasting crises in the neonatal period. False positives are common in premature infants due to immature enzyme systems. Positive screens require immediate confirmatory testing and potential treatment initiation.
Usage
Usage note: Always specify the condition being screened for, as newborn screening covers multiple conditions.
In Context
- "The patient's CAH newborn screening was positive, prompting immediate endocrine consultation." — Clinical documentation
- "CAH newborn screening programs have significantly reduced mortality from salt-wasting crises." — Medical review article
Also known as
17-OHP screening
neonatal CAH screening
Don't confuse with
general newborn screening
thyroid screening