meconium ileus
Pronunciation: meh-KOH-nee-um IL-ee-us
Intestinal obstruction in newborns caused by abnormally thick meconium, often associated with cystic fibrosis.
Full Definition
Meconium ileus is a form of intestinal obstruction that occurs in newborns when thick, sticky meconium (first stool) blocks the small intestine, typically at the level of the ileum. This condition is strongly associated with cystic fibrosis, occurring in approximately 15-20% of infants with CF. The obstruction presents with abdominal distension, bilious vomiting, and failure to pass meconium. Treatment may involve contrast enemas or surgical intervention. The condition requires immediate recognition as it may be the first sign of cystic fibrosis.
Usage
Usage note: The term 'meconium' should not be capitalized unless beginning a sentence.
In Context
- "The diagnosis of meconium ileus prompted immediate cystic fibrosis genetic testing and sweat chloride analysis." — Neonatal intensive care unit note