Intermediate
Technical
In the Industry Vocabulary Test
immunophenotyping
Flow cytometric analysis of immune cell surface markers to characterize and quantify lymphocyte populations.
Full Definition
Immunophenotyping is a laboratory technique that uses flow cytometry with fluorescently labeled antibodies to identify and quantify specific immune cell populations based on their surface marker expression. In pediatric immunology, it is essential for diagnosing primary immunodeficiencies, monitoring immune reconstitution after transplantation, and assessing treatment responses. The technique can identify T-cell subsets, B-cell populations, NK cells, and their functional states.
Usage
Usage note: Use as a single word; avoid hyphenation. Often abbreviated as 'phenotyping' in clinical contexts.
In Context
- "Immunophenotyping revealed absent CD19+ B cells, confirming the diagnosis of X-linked agammaglobulinemia." — Laboratory report
- "Serial immunophenotyping monitored T-cell recovery following hematopoietic stem cell transplantation." — Clinical monitoring
Also known as
flow cytometric immunophenotyping
lymphocyte subset analysis
Don't confuse with
immunohistochemistry
cytogenetics