Urinary Tract Infection Prophylaxis
Long-term low-dose antibiotics used to prevent recurrent UTIs in children with urological abnormalities.
Full Definition
Urinary tract infection prophylaxis involves daily administration of low-dose antibiotics, typically trimethoprim-sulfamethoxazole or nitrofurantoin, to prevent recurrent UTIs in high-risk pediatric patients. It is primarily used in children with vesicoureteral reflux, neurogenic bladder, or other urological abnormalities that predispose to infection. The practice remains controversial, with current guidelines emphasizing individualized risk assessment and consideration of factors such as patient age, reflux grade, and breakthrough infection history.
Usage
Usage note: Current guidelines emphasize individualized decision-making rather than routine use.
In Context
- "Urinary tract infection prophylaxis was initiated following the third febrile UTI." — Pediatric urology note
- "The effectiveness of urinary tract infection prophylaxis was questioned after breakthrough infections." — Clinical review note