physiologic jaundice
Normal yellowing of a newborn's skin and eyes occurring in the first week of life due to immature liver function and increased bilirubin production.
Full Definition
Physiologic jaundice is a benign condition affecting approximately 60% of term newborns and 80% of preterm infants, typically appearing on day 2-3 of life. It results from the combination of increased bilirubin production from red blood cell breakdown and the newborn's immature hepatic conjugation system. Unlike pathologic jaundice, it follows a predictable pattern, peaks by day 3-5, and resolves spontaneously by 1-2 weeks in term infants. Clinical editors should distinguish this from concerning jaundice that appears within 24 hours of birth or persists beyond expected timeframes.
Usage
Usage note: Always distinguish from pathologic jaundice in clinical documentation; timing and progression are key differentiators.
In Context
- "The discharge summary noted that the infant developed mild physiologic jaundice on day 3, which was expected to resolve without intervention." — Hospital discharge documentation
- "Parent education materials should differentiate between normal physiologic jaundice and concerning signs requiring immediate evaluation." — Patient education materials