Intermediate
Technical
IVT
glomerular filtration rate
A measure of kidney function indicating how much blood the kidneys filter per minute, critical for assessing renal impairment in children.
Full Definition
Glomerular filtration rate (GFR) is a key indicator of kidney function that measures the volume of filtrate formed per minute by the kidneys. In pediatric nephrology, GFR is typically estimated using formulas that account for a child's height, serum creatinine, and age. Normal GFR values vary significantly with age and body size in children, making age-appropriate reference ranges essential for accurate assessment. Reduced GFR indicates kidney dysfunction and guides treatment decisions.
Usage
Usage note: Always specify units (mL/min/1.73m²) and note age-appropriate normal ranges in pediatric contexts.
In Context
- "The patient's estimated glomerular filtration rate of 45 mL/min/1.73m² indicated stage 3 chronic kidney disease." — Clinical assessment report
- "Serial monitoring of glomerular filtration rate is essential in children receiving nephrotoxic medications." — Treatment protocol
Also known as
GFR
estimated glomerular filtration rate
eGFR
Don't confuse with
creatinine clearance