hypertensive nephrosclerosis

Full Definition

Hypertensive nephrosclerosis is kidney damage resulting from prolonged elevated blood pressure, causing arteriolar sclerosis, glomerulosclerosis, and tubulointerstitial fibrosis. While less common in pediatric patients than adults, it can occur in children with severe or poorly controlled hypertension from conditions such as renal artery stenosis or coarctation of the aorta. Early recognition and blood pressure control are crucial to prevent progressive renal dysfunction.

Usage

Usage note: More common in adults but can occur in pediatric hypertension.

In Context

• "Renal biopsy confirmed hypertensive nephrosclerosis in this adolescent with malignant hypertension." — Pathology report
• "Prevention of hypertensive nephrosclerosis requires strict blood pressure control from early childhood." — Clinical guideline