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renal tubular acidosis
A group of disorders characterized by the kidney's inability to acidify urine appropriately, leading to metabolic acidosis.
Full Definition
Renal tubular acidosis (RTA) encompasses several inherited or acquired disorders where the kidneys cannot properly acidify urine despite normal or near-normal glomerular filtration rates. In pediatric patients, RTA can lead to failure to thrive, nephrocalcinosis, and progressive chronic kidney disease if untreated. The condition is classified into different types based on the specific tubular defect involved.
Usage
Usage note: Often abbreviated as RTA in clinical documentation.
In Context
- "The patient's persistent metabolic acidosis with normal anion gap suggested renal tubular acidosis." — Clinical case report
- "Growth retardation in this infant prompted investigation for renal tubular acidosis." — Pediatric assessment
Also known as
RTA
Don't confuse with
renal tubular necrosis
acute tubular necrosis