urea reduction ratio
A measure of dialysis adequacy calculated from pre- and post-dialysis blood urea nitrogen levels, critical for monitoring pediatric dialysis patients.
Full Definition
Urea reduction ratio (URR) quantifies the effectiveness of a single dialysis session by measuring the percentage reduction in blood urea nitrogen from pre- to post-dialysis. The calculation is: URR = [(pre-dialysis BUN - post-dialysis BUN) / pre-dialysis BUN] × 100. In pediatric dialysis, target URR should exceed 65%, though higher targets may be appropriate for growing children. URR is used alongside Kt/V measurements to ensure adequate solute clearance and optimal growth and development in pediatric patients requiring renal replacement therapy.
Usage
Usage note: Specify target values appropriate for pediatric populations and link to growth and development outcomes.
In Context
- "The urea reduction ratio of 72% indicated adequate dialysis delivery for this 10-year-old patient." — Dialysis adequacy assessment
- "Poor growth prompted evaluation of dialysis adequacy, revealing a suboptimal urea reduction ratio of 58%." — Clinical monitoring report