Intermediate
Technical
In the Industry Vocabulary Test
breakthrough seizure
A seizure that occurs in a patient whose epilepsy has been previously well-controlled with medication.
Full Definition
Breakthrough seizures represent a temporary loss of seizure control in patients with previously stable epilepsy. Common causes include medication non-compliance, drug interactions, illness with fever, sleep deprivation, stress, or changes in antiepileptic drug levels. Isolated breakthrough seizures may not require immediate medication changes, but recurrent episodes warrant investigation and potential treatment adjustment. Documentation should include precipitating factors and seizure characteristics to guide management decisions.
Usage
Usage note: Two words with hyphen when used as compound modifier, otherwise separate words.
In Context
- "The patient experienced a breakthrough seizure after missing two doses of levetiracetam." — Emergency visit note
- "Family was counseled about potential triggers for breakthrough seizures during illness." — Patient education
Also known as
rescue seizure
Contrasted with
well-controlled seizure
Don't confuse with
new-onset seizure
withdrawal seizure