infantile spasms
A specific type of epileptic seizure characterized by brief, symmetric contractions of neck, trunk, and extremities in infants.
Full Definition
Infantile spasms, also known as West syndrome when associated with hypsarrhythmia and developmental regression, typically occur between 3-12 months of age. The spasms appear as sudden flexion or extension movements, often occurring in clusters upon awakening. This condition represents an epileptic encephalopathy requiring urgent treatment with ACTH, vigabatin, or corticosteroids. Early recognition and treatment are crucial for optimizing developmental outcomes.
Usage
Usage note: Two words, not hyphenated. Distinguish from other movement disorders in infants.
In Context
- "The 8-month-old presented with clusters of infantile spasms and developmental regression." — Consultation note
- "EEG confirmed hypsarrhythmia pattern consistent with infantile spasms syndrome." — Diagnostic report