perinatal stroke
A cerebrovascular event occurring between 20 weeks gestation and 28 days postnatal age, often presenting with seizures in the neonatal period.
Full Definition
Perinatal stroke encompasses both fetal and neonatal stroke occurring from 20 weeks of gestation through the first 28 days of life. These strokes can be arterial or venous in nature and may occur in utero, during delivery, or in the early neonatal period. Presentation is often subtle, with neonatal seizures being the most common presenting symptom. Many cases are not recognized until months later when asymmetric motor development or hand preference becomes apparent. Risk factors include birth asphyxia, congenital heart disease, infection, and prothrombotic conditions.
Usage
Usage note: Often not diagnosed until motor asymmetries develop; distinguish from HIE which has a different pattern of injury.
In Context
- "The newborn's focal seizures prompted neuroimaging which revealed perinatal stroke affecting the left MCA territory." — Neonatal intensive care note
- "At 6 months, the infant showed right-sided weakness consistent with perinatal stroke." — Pediatric neurology follow-up