leukocoria
Pronunciation: loo-koh-KOR-ee-ah
White pupillary reflex in infants and children that may indicate serious ocular pathology requiring urgent evaluation.
Full Definition
Leukocoria, or "white pupil," is an abnormal white or grayish-white reflection from the pupil that replaces the normal red reflex. This clinical sign can indicate various serious conditions including retinoblastoma, congenital cataracts, retinal detachment, or Coats disease. Early recognition is crucial as some causes, particularly retinoblastoma, are life-threatening and require immediate intervention. The condition is often first noticed in photographs where one pupil appears white instead of showing the typical red-eye effect.
Usage
Usage note: Always spelled with 'leuko-' prefix, not 'leuco-' despite some variant spellings in literature.
In Context
- "The pediatric ophthalmologist immediately referred the infant for urgent imaging after detecting leukocoria during routine screening." — clinical examination report
- "Parents should be educated to watch for leukocoria in flash photography as an early sign of ocular pathology." — patient education material