Maceration
Pronunciation: mak-uh-RAY-shun
Post-mortem softening, discolouration, and skin slippage of fetal tissues resulting from autolysis in utero after fetal death.
Full Definition
Maceration refers to the sterile autolytic changes that occur in a fetus retained in utero after intrauterine fetal demise (IUFD). It is characterised by skin slippage, brownish-red discolouration, softening of viscera, and eventual liquefaction of soft tissues. Pathologists grade maceration severity to estimate the post-mortem interval before delivery, which assists in determining the timing of fetal death. Grading scales (e.g., Genest scale) assign stages I–III based on the extent of skin and organ changes. Editors should note that 'maceration' in this context is distinct from its use in dermatology to describe skin softening from moisture exposure.
Usage
Usage note: Always specify the maceration grade or stage when used in a fetal autopsy report; the unqualified term alone is insufficient for clinical documentation.
In Context
- "Grade II maceration was noted, consistent with fetal death occurring approximately 48–72 hours prior to delivery." — Fetal autopsy report
- "Histological assessment was limited by advanced maceration of the hepatic tissue." — Pathology report addendum