necrotizing enterocolitis
A serious gastrointestinal condition affecting premature infants, characterized by intestinal tissue death.
Full Definition
Necrotizing enterocolitis (NEC) is a devastating gastrointestinal emergency that primarily affects premature infants, particularly those born before 32 weeks gestation. The condition involves inflammation and subsequent necrosis of intestinal tissue, most commonly affecting the terminal ileum and ascending colon. NEC can progress rapidly from feeding intolerance to bowel perforation and sepsis. Risk factors include prematurity, formula feeding, and compromised intestinal blood flow. The condition requires immediate medical intervention and may necessitate surgical resection of necrotic bowel segments.
Usage
Usage note: Always spell out fully on first mention, followed by abbreviation NEC in parentheses.
In Context
- "The pathology report confirmed necrotizing enterocolitis with full-thickness bowel wall necrosis." — Pathology report
- "Serial abdominal radiographs showed progression of necrotizing enterocolitis with pneumatosis intestinalis." — Clinical documentation