retinopathy of prematurity
An eye disorder affecting premature infants, characterized by abnormal blood vessel development in the retina.
Full Definition
Retinopathy of prematurity (ROP) is a potentially blinding eye disorder that affects premature infants, particularly those born before 31 weeks gestation or weighing less than 1,250 grams. The condition occurs when normal retinal blood vessel development is disrupted, leading to abnormal vascular proliferation that can progress to retinal detachment. ROP is classified into five stages of increasing severity, from mild vascular abnormalities (Stage 1) to complete retinal detachment (Stage 5). The condition is further characterized by zone (location) and presence of plus disease (vascular dilation and tortuosity). Risk factors include extreme prematurity, prolonged oxygen exposure, and various neonatal complications.
Usage
Usage note: Formerly known as retrolental fibroplasia; current terminology preferred.
In Context
- "Ophthalmological examination revealed Stage 3 retinopathy of prematurity with plus disease in Zone 2." — Clinical report
- "The patient developed severe retinopathy of prematurity requiring laser photocoagulation therapy." — Treatment documentation