bronchial hyperresponsiveness
Exaggerated bronchoconstrictive response to stimuli, a hallmark feature of asthma in children requiring specialized testing.
Full Definition
Bronchial hyperresponsiveness (BHR) refers to the tendency of airways to narrow excessively in response to various stimuli such as allergens, cold air, exercise, or pharmacologic agents like methacholine. This condition is fundamental to asthma pathophysiology and can be measured through bronchial challenge testing using methacholine or exercise protocols. In pediatric patients, BHR assessment helps distinguish asthma from other causes of respiratory symptoms and guides treatment decisions. The degree of hyperresponsiveness often correlates with asthma severity and may persist even when symptoms are controlled.
Usage
Usage note: Often abbreviated as BHR in clinical documentation. Key concept in asthma diagnosis and management.
In Context
- "Methacholine challenge testing confirmed significant bronchial hyperresponsiveness consistent with asthma diagnosis." — Pulmonary function report
- "The patient's bronchial hyperresponsiveness improved following three months of inhaled corticosteroid therapy." — Follow-up assessment