positive end-expiratory pressure
Pronunciation: POZ-i-tiv end ik-SPY-ruh-tawr-ee PRESH-er
Pressure maintained in airways at the end of expiration during mechanical ventilation to prevent alveolar collapse.
Full Definition
Positive end-expiratory pressure (PEEP) is a ventilatory strategy that maintains a predetermined pressure level in the airways and alveoli at the end of expiration, preventing complete alveolar deflation and promoting recruitment of collapsed lung units. PEEP improves oxygenation by increasing functional residual capacity, reducing ventilation-perfusion mismatch, and preventing cyclic opening and closing of alveoli (atelectrauma). In pediatric mechanical ventilation, PEEP levels typically range from 3-12 cmH2O, depending on the underlying pathology and patient condition. While beneficial for gas exchange, excessive PEEP can impair venous return and cardiac output, requiring careful titration based on clinical response.
Usage
Usage note: Always abbreviated as PEEP in clinical practice; specify pressure level in cmH2O.
In Context
- "PEEP was increased from 5 to 8 cmH2O to improve oxygenation in the patient with ARDS." — Ventilator adjustment note
- "The optimal positive end-expiratory pressure was determined using a PEEP titration study." — ICU management plan