tracheal agenesis
Pronunciation: tray-KEE-ul ay-JEN-uh-sis
A rare, usually fatal congenital anomaly in which the trachea is absent or severely underdeveloped, typically associated with other major structural malformations.
Full Definition
Tracheal agenesis is classified by the Floyd system (Types I–III) according to the degree of tracheal absence and the relationship of the bronchi to the oesophagus. Type II, in which a short tracheal remnant opens into the oesophagus, is the most common subtype. The condition is almost always incompatible with life without immediate surgical intervention, and even with surgery, survival is rare. Editors should note that 'agenesis' (complete absence) must not be conflated with 'atresia' (closure or absence of a lumen) or 'stenosis' (narrowing); though sometimes used interchangeably in lay contexts, these are distinct anatomical entities in specialist copy.
Usage
Usage note: Do not substitute 'atresia' for 'agenesis'. The Floyd classification (Type I, II, III) should use Roman numerals per surgical convention.
In Context
- "The autopsy confirmed Type II tracheal agenesis, with both bronchi arising directly from the oesophagus." — Paediatric pathology case report
- "Tracheal agenesis must be distinguished from tracheal stenosis in both the clinical and editorial review of congenital airway anomaly reports." — Review article on congenital airway anomalies