Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis
Also written as: PFAPA — Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis
A periodic fever syndrome characterized by recurrent episodes of fever with oral ulcers, sore throat, and swollen lymph nodes in children.
Full Definition
Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis (PFAPA) is an autoinflammatory disorder typically affecting young children. Episodes occur at regular intervals, usually every 3-6 weeks, lasting 3-5 days. The condition is distinguished from other periodic fever syndromes by its predictable pattern and specific constellation of symptoms. Treatment often involves corticosteroids for acute episodes, with tonsillectomy considered for frequent recurrences.
Usage
Usage note: Often abbreviated as PFAPA in clinical documentation; ensure full form is provided on first use in patient materials.
In Context
- "The patient presented with classic PFAPA syndrome features including predictable fever cycles and oral aphthous ulcers." — Clinical case report
- "Unlike familial Mediterranean fever, PFAPA syndrome typically begins in early childhood and has a more predictable pattern." — Differential diagnosis documentation