choriocarcinoma
Pronunciation: kor-ee-oh-kar-si-NOH-muh
Malignant tumor arising from trophoblastic tissue, most commonly following molar pregnancy, abortion, or normal pregnancy.
Full Definition
Choriocarcinoma is a highly aggressive malignant tumor that develops from trophoblastic cells, which normally form part of the placenta. This rare cancer can occur after any type of pregnancy, including normal deliveries, miscarriages, ectopic pregnancies, or molar pregnancies. Choriocarcinoma is characterized by its tendency to metastasize early, particularly to the lungs, liver, and brain. The tumor produces high levels of human chorionic gonadotropin (hCG), which serves as a tumor marker for diagnosis and monitoring treatment response.
Usage
Usage note: Part of gestational trophoblastic disease spectrum. Ensure proper spelling - note 'carcin' not 'carsin'.
In Context
- "Persistent elevation of hCG levels raised suspicion for choriocarcinoma following molar pregnancy." — Oncology consultation note
- "Chest imaging revealed pulmonary metastases consistent with choriocarcinoma spread." — Radiology report