Guided Bone Regeneration
Also written as: GBR — Guided Bone Regeneration
A surgical technique using barrier membranes to exclude non-osteogenic cells and allow selective repopulation of a bone defect by osteogenic cells. Abbreviated GBR.
Full Definition
Guided Bone Regeneration (GBR) is a procedure in which a physical barrier membrane is placed over an osseous defect to prevent ingrowth of epithelial and connective tissue cells, thereby creating a protected space for osteogenic progenitor cells to regenerate bone. GBR is frequently combined with bone-grafting materials in both periodontal and implant-site development contexts. Editors must distinguish GBR from Guided Tissue Regeneration (GTR), which targets periodontal attachment regeneration rather than pure bone volume augmentation. Membranes used in GBR may be resorbable or non-resorbable, a distinction often relevant in materials-and-methods sections.
Usage
Usage note: Do not substitute GBR for GTR or vice versa; they target different tissue types. Expand abbreviation on first use.
In Context
- "GBR was performed simultaneously with implant placement using a resorbable collagen membrane and xenograft particulate." — Implant surgery report
- "The manuscript used GBR and GTR interchangeably, which the editor flagged as a clinical inaccuracy." — Peer review editorial note