PKU
Pronunciation: P-K-U
Also written as: PKU — Phenylketonuria
Phenylketonuria screening test performed on newborns using heel stick blood collected on filter paper cards.
Full Definition
PKU testing is part of mandatory newborn screening programs designed to detect phenylketonuria, a genetic disorder affecting amino acid metabolism. The test requires collection of capillary blood from a heel stick procedure, typically performed 24-48 hours after birth when the infant has consumed protein. Blood is applied to specific areas on standardized filter paper cards, which must be completely saturated and allowed to air dry. Proper timing, collection technique, and card handling are crucial for accurate results. The screening also tests for other metabolic disorders and requires careful documentation of collection time, infant age, and feeding status.
Usage
Usage note: Always document collection time and infant's age in hours when performing PKU screening
In Context
- "PKU screening was collected via heel stick at 36 hours of age with adequate blood saturation on all circles." — Newborn screening documentation
- "The PKU card was rejected due to insufficient blood volume in circle 3, requiring recollection." — Laboratory rejection notice