ALCL
Also written as: ALCL — Anaplastic Large Cell Lymphoma
Anaplastic large cell lymphoma, a rare cancer associated with textured breast implants.
Full Definition
Anaplastic large cell lymphoma (ALCL) is a rare form of T-cell lymphoma that has been associated with textured breast implants, termed breast implant-associated anaplastic large cell lymphoma (BIA-ALCL). This condition typically presents as a late seroma, mass, or capsular contracture years after implantation. Diagnosis requires immunohistochemistry, and treatment usually involves complete implant removal with total capsulectomy. The condition has led to significant changes in implant selection and patient counseling practices.
Usage
Usage note: When referring to breast implant-associated cases, use 'BIA-ALCL' for clarity.
In Context
- "The patient developed a late seroma concerning for possible ALCL fifteen years post-augmentation." — Oncology referral letter
- "CD30 immunostaining was positive, confirming the diagnosis of ALCL." — Pathology report