Intermediate
Technical
In the Industry Vocabulary Test
liquid biopsy
A minimally invasive test that analyzes circulating tumor DNA or cells in blood samples.
Full Definition
Liquid biopsy represents a revolutionary approach to cancer monitoring that analyzes circulating tumor DNA, circulating tumor cells, or extracellular vesicles present in blood or other bodily fluids. This technology enables real-time monitoring of tumor dynamics, early detection of resistance mutations, and assessment of treatment response without requiring invasive tissue procedures. The method is particularly valuable for monitoring disease progression and guiding therapeutic adjustments.
Usage
Usage note: Always hyphenate when used as compound modifier. Distinguish from traditional blood tests.
In Context
- "Serial liquid biopsy monitoring detected emerging resistance mutations before radiographic progression." — Clinical monitoring report
- "The liquid biopsy failed to detect circulating tumor DNA due to low tumor burden." — Laboratory result interpretation
Also known as
ctDNA analysis
blood-based biopsy
Contrasted with
tissue biopsy
surgical biopsy
Don't confuse with
blood test
serum marker