chorionic villus sampling
Pronunciation: KOR-ee-on-ik VIL-us SAM-pling
Invasive diagnostic procedure involving biopsy of placental tissue to detect fetal genetic abnormalities, typically performed between 10-13 weeks of pregnancy.
Full Definition
Chorionic villus sampling (CVS) is an invasive prenatal diagnostic test that involves taking a small sample of chorionic villi from the placenta for genetic analysis. The procedure can be performed either transcervically or transabdominally under ultrasound guidance, typically between 10-13 weeks of gestation. Unlike amniocentesis, CVS provides earlier diagnosis but cannot detect neural tube defects. The sample contains the same genetic material as the fetus and can detect chromosomal abnormalities, genetic disorders, and other conditions. Results are available earlier in pregnancy, allowing for more treatment options if abnormalities are detected.
Usage
Usage note: Often abbreviated as CVS in clinical documentation.
In Context
- "The patient elected to undergo chorionic villus sampling at 11 weeks gestation due to advanced maternal age." — Medical report
- "Chorionic villus sampling results revealed a normal 46,XX karyotype." — Laboratory report