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Advanced Technical In the Industry Vocabulary Test

fetal fibronectin

Pronunciation: FEE-tal fy-broh-NEK-tin

Also written as: fFN

Glycoprotein found at the interface between fetal membranes and maternal decidua, used as a biomarker for preterm labor risk.

Full Definition

Fetal fibronectin (fFN) is a glycoprotein normally present at the maternal-fetal interface that acts as an adhesive between the fetal membranes and maternal decidua. When detected in cervicovaginal secretions after 22 weeks gestation, it may indicate disruption of this interface and increased risk of preterm delivery. The fetal fibronectin test is used primarily as a negative predictor - a negative result provides reassurance that delivery is unlikely within the next 7-14 days.

Usage

Usage note: Commonly abbreviated as fFN; results interpreted in conjunction with clinical findings.

In Context

  • "The negative fetal fibronectin test provided reassurance that preterm delivery was unlikely in the next two weeks." — Preterm labor evaluation
  • "Given the positive fetal fibronectin and short cervix, steroids were administered for fetal lung maturation." — High-risk obstetric management

Also known as

fFN fibronectin test preterm labor marker

Don't confuse with

cervical length phosphorylated insulin-like growth factor binding protein-1
fetal echocardiography ← Back to glossary Fetal growth percentile

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