Multiple of the median
Also written as: MoM — Multiple of the median
Statistical method for expressing maternal serum analyte levels relative to gestational age-specific reference values.
Full Definition
Multiple of the median (MoM) is a standardized way of reporting maternal serum screening results by expressing the measured analyte concentration as a ratio compared to the median value for the specific gestational age. This normalization allows for consistent interpretation across different laboratories and gestational ages. MoM values are adjusted for maternal factors such as weight, race, diabetes status, and smoking to improve screening accuracy. Values typically range from 0.5 to 2.0 MoM, with results outside this range potentially indicating increased risk for chromosomal abnormalities or neural tube defects.
Usage
Usage note: Commonly abbreviated as MoM. Note singular 'median' not 'medians' in full form. Lowercase when writing out in full.
In Context
- "The AFP level of 2.3 multiple of the median warrants further evaluation for neural tube defects." — Screening test interpretation
- "All analyte results are reported as multiple of the median values adjusted for maternal characteristics." — Laboratory protocol