cardiotoxicity
Heart damage or dysfunction caused by medications, chemicals, or other therapeutic interventions.
Full Definition
Cardiotoxicity refers to heart damage or dysfunction that results from exposure to medications, chemicals, radiation, or other therapeutic interventions. This is particularly relevant in oncology where chemotherapeutic agents, targeted therapies, and radiation can cause acute or chronic cardiac complications. Manifestations may include cardiomyopathy, heart failure, arrhythmias, pericardial disease, or coronary artery disease. Prevention and early detection through cardiovascular monitoring before, during, and after potentially cardiotoxic treatments is essential. The field of cardio-oncology specifically addresses these concerns.
Usage
Usage note: Specify the causative agent when documenting cardiotoxicity.
In Context
- "Baseline echocardiography was performed to monitor for potential cardiotoxicity before starting chemotherapy." — cardio-oncology consultation
- "The patient developed evidence of cardiotoxicity after six months of targeted therapy." — oncology treatment note