lipid apheresis
Extracorporeal procedure that selectively removes atherogenic lipoproteins from blood plasma in patients with severe dyslipidemia.
Full Definition
Lipid apheresis is a specialized extracorporeal treatment that mechanically removes low-density lipoprotein cholesterol, lipoprotein(a), and other atherogenic particles from the patient's blood. This procedure is typically reserved for patients with homozygous familial hypercholesterolemia or severe heterozygous familial hypercholesterolemia who cannot achieve target lipid levels despite maximally tolerated statin therapy. The treatment involves drawing blood from the patient, processing it through specialized columns or filters to remove specific lipoproteins, and returning the treated plasma to the patient. Sessions typically occur every 1-2 weeks and can reduce LDL cholesterol by 60-80% acutely.
Usage
Usage note: Capitalize when referring to specific FDA-approved devices (e.g., Liposorber). Lowercase for the general procedure.
In Context
- "The patient was referred for lipid apheresis after failing to achieve target LDL levels despite maximally tolerated combination therapy." — Cardiology consultation note
- "Insurance coverage for lipid apheresis requires documentation of inadequate response to pharmacological interventions." — Prior authorization request