lipid triad
A pattern of dyslipidemia characterized by elevated triglycerides, low HDL cholesterol, and small dense LDL particles.
Full Definition
The lipid triad represents a specific dyslipidemic pattern commonly seen in metabolic syndrome and type 2 diabetes. It consists of elevated triglycerides (>150 mg/dL), low HDL cholesterol (<40 mg/dL in men, <50 mg/dL in women), and predominance of small, dense LDL particles. This pattern is associated with increased cardiovascular risk beyond what traditional LDL cholesterol levels might suggest. Recognition of this triad helps clinicians identify patients who may benefit from targeted therapies such as fibrates or combination lipid-lowering therapy.
Usage
Usage note: Often capitalized in formal medical writing; avoid using interchangeably with general dyslipidemia.
In Context
- "The patient's lipid profile demonstrated the classic lipid triad with triglycerides of 280 mg/dL, HDL of 32 mg/dL, and predominantly small dense LDL particles." — Clinical assessment report
- "Presence of the lipid triad warranted consideration of fibrate therapy in addition to statin treatment." — Treatment plan documentation