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Professional Technical IVT

TEAE

Also written as: TEAE — Treatment-Emergent Adverse Event

An adverse event that emerges during treatment or worsens from baseline after treatment initiation.

Full Definition

A Treatment-Emergent Adverse Event (TEAE) refers to any adverse event that begins or worsens after the first dose of study medication. This includes events that were absent at baseline and develop during treatment, or pre-existing conditions that worsen in severity or frequency. TEAEs are distinguished from adverse events present at baseline to establish causality with the intervention. In psychiatric research, careful documentation of TEAEs is crucial for safety monitoring, particularly given the complex side effect profiles of psychotropic medications.

Usage

Usage note: Always capitalize as TEAE when used as acronym; spell out on first use in documents.

In Context

  • "The most common TEAE in the antidepressant group was nausea, occurring in 23% of participants." — Clinical trial safety report
  • "All TEAEs were coded using MedDRA terminology and assessed for severity and relationship to study drug." — Regulatory submission document

Also known as

treatment-related adverse event emergent side effect

Contrasted with

pre-treatment adverse event baseline condition

Don't confuse with

adverse event serious adverse event treatment-emergent adverse event
tardive dyskinesia ← Back to glossary time-to-event analysis

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