therapeutic hold
Temporary cessation of a medication or treatment intervention to assess baseline functioning or evaluate adverse effects.
Full Definition
A therapeutic hold involves the temporary discontinuation of a medication or treatment intervention for clinical assessment purposes, typically to evaluate baseline functioning, assess potential adverse effects, or determine the ongoing necessity of the treatment. Unlike permanent discontinuation, therapeutic holds are planned, time-limited interruptions with specific monitoring protocols and predetermined criteria for resumption. Common reasons include distinguishing medication side effects from underlying symptoms, assessing organ function during potential toxicity, or evaluating whether symptom improvement is sustained without ongoing treatment. The duration and monitoring requirements vary based on the medication's half-life, potential withdrawal effects, and clinical indication.
Usage
Usage note: Specify duration, monitoring plan, and criteria for treatment resumption.
In Context
- "A therapeutic hold of the antipsychotic medication was initiated to assess whether tremors were medication-related." — Medication management note
- "The two-week therapeutic hold confirmed that cognitive improvements were sustained without stimulant medication." — ADHD treatment assessment