CATIE study
Pronunciation: KAY-tie
Also written as: CATIE — Clinical Antipsychotic Trials of Intervention Effectiveness
Landmark clinical trial comparing the effectiveness of antipsychotic medications for schizophrenia treatment.
Full Definition
The Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) was a large-scale, federally funded clinical trial conducted from 2001 to 2004 that compared the effectiveness of older and newer antipsychotic medications in treating schizophrenia. The study followed 1,493 patients across multiple sites and found that older, less expensive medications were often as effective as newer, more costly atypical antipsychotics. CATIE's findings significantly influenced prescribing practices and treatment guidelines in psychiatry. The study's methodology and results are frequently referenced in clinical decision-making, treatment protocols, and medication management discussions in psychiatric settings.
Usage
Usage note: Capitalize all letters; reference specific findings when citing
In Context
- "The medication selection follows CATIE study recommendations for first-line antipsychotic treatment." — Treatment planning documentation
- "CATIE study data supports the use of perphenazine as an equally effective alternative to newer antipsychotics." — Clinical guideline reference