lorazepam
Pronunciation: lor-AZ-eh-pam
A short-acting benzodiazepine commonly used for anxiety, agitation, and seizure management in psychiatric settings.
Full Definition
Lorazepam is a short- to intermediate-acting benzodiazepine medication frequently used in psychiatric practice for the management of acute anxiety, agitation, panic attacks, and as an adjunct in treating alcohol withdrawal and seizures. Known by the brand name Ativan, lorazepam works by enhancing the activity of gamma-aminobutyric acid (GABA) in the brain, producing sedative, anxiolytic, and muscle relaxant effects. Its relatively predictable pharmacokinetics and availability in multiple formulations (oral, sublingual, intramuscular, and intravenous) make it particularly useful in emergency psychiatric situations. The medication carries risks of tolerance, dependence, and withdrawal symptoms with prolonged use.
Usage
Usage note: Always include dosage and route when documenting; monitor for signs of dependence with long-term use.
In Context
- "The patient received 2 mg lorazepam intramuscularly for severe agitation in the emergency department." — Emergency treatment note
- "Lorazepam was titrated to 1 mg three times daily for ongoing anxiety management." — Medication adjustment note