pseudodementia
Pronunciation: SOO-doh-duh-MEN-sha
Cognitive impairment associated with depression that mimics dementia but is potentially reversible with treatment.
Full Definition
Pseudodementia, also known as depressive pseudodementia, refers to cognitive symptoms that occur in the context of major depression and superficially resemble dementia but are potentially reversible with appropriate treatment of the underlying mood disorder. Unlike true dementia, pseudodementia typically features more prominent subjective complaints of memory loss, variable cognitive performance, and preserved insight into deficits. Patients may exhibit apathy, poor concentration, and apparent memory problems that improve significantly with antidepressant treatment. Careful neuropsychological testing and clinical evaluation are essential to distinguish this condition from early-stage dementia.
Usage
Usage note: Term is somewhat controversial; some prefer 'depression-related cognitive impairment'.
In Context
- "Neuropsychological testing suggested pseudodementia rather than early Alzheimer's disease." — Neuropsychological evaluation report
- "The patient's cognitive symptoms completely resolved following successful treatment of pseudodementia." — Treatment outcome summary