extrapyramidal symptoms
Also written as: EPS — Extrapyramidal Symptoms
Movement disorders caused by antipsychotic medications affecting the brain's motor control systems.
Full Definition
Extrapyramidal symptoms (EPS) are a group of movement disorders that commonly occur as side effects of antipsychotic medications. They result from blockade of dopamine receptors in the nigrostriatal pathway. EPS include acute dystonia (muscle spasms), parkinsonism (tremor, rigidity, bradykinesia), akathisia (restlessness), and tardive dyskinesia (late-onset involuntary movements). These symptoms can significantly impact quality of life and medication compliance. Risk factors include high-potency antipsychotics, higher doses, and individual susceptibility. Treatment may involve dose reduction, medication switching, or anticholinergic agents for acute symptoms.
Usage
Usage note: EPS is widely accepted abbreviation in psychiatric documentation.
In Context
- "The patient developed extrapyramidal symptoms within 48 hours of starting haloperidol." — adverse event documentation
- "Regular monitoring for extrapyramidal symptoms is essential with typical antipsychotics." — medication monitoring plan