anticholinergic
Describes effects or agents that block acetylcholine receptors, often causing dry mouth, constipation, and cognitive impairment.
Full Definition
Refers to pharmacological effects or medications that block acetylcholine receptors in the nervous system. Anticholinergic effects are common side effects of many psychiatric medications, particularly tricyclic antidepressants and some antipsychotics. These effects include dry mouth, constipation, urinary retention, blurred vision, and cognitive impairment. The term is crucial for editors reviewing clinical documentation as it describes both therapeutic effects (when intentional) and adverse effects (when unwanted).
Usage
Usage note: Often abbreviated as 'anticholinergic effects' in clinical writing. Distinguish from antihistaminic effects.
In Context
- "The patient experienced significant anticholinergic effects including dry mouth and constipation after starting amitriptyline." — Clinical case report
- "Elderly patients are particularly vulnerable to anticholinergic toxicity from psychiatric medications." — Medical review article