GABA-ergic

Full Definition

Relating to or affecting gamma-aminobutyric acid (GABA) neurotransmitter systems in the brain. GABA is the primary inhibitory neurotransmitter, and GABA-ergic medications typically have sedating, anxiolytic, anticonvulsant, or muscle relaxant properties. In psychopharmacology, GABA-ergic drugs include benzodiazepines, barbiturates, some anticonvulsants used as mood stabilizers, and certain sleep medications. Editors should note the hyphenation and understand that enhancement of GABA activity generally produces calming effects.

Usage

Usage note: Can be written as 'GABAergic' (no hyphen) or 'GABA-ergic' (with hyphen) - both are acceptable.

In Context

• "The medication's GABA-ergic properties explained its sedating and anxiolytic effects." — Pharmacology textbook
• "GABA-ergic enhancement is the primary mechanism for most anti-anxiety medications." — Medical journal article