acute toxicity
Side effects from radiation therapy that occur during or shortly after treatment completion.
Full Definition
Acute toxicity refers to side effects that develop during radiation therapy or within 90 days of treatment completion. These reactions are typically caused by rapid cell division in normal tissues exposed to radiation, such as skin, mucous membranes, and gastrointestinal tract. Common acute toxicities include radiation dermatitis, mucositis, fatigue, and organ-specific effects depending on the treatment site.
Usage
Usage note: Contrasted with 'late toxicity' which appears months to years after treatment.
In Context
- "The patient experienced grade 2 acute toxicity manifesting as esophagitis." — Weekly assessment note
- "Acute toxicity monitoring is essential during head and neck radiation treatments." — Clinical protocol