clinical target volume
Also written as: CTV — Clinical Target Volume
The anatomical volume that contains the gross tumor and areas at risk for microscopic disease spread.
Full Definition
In radiation oncology treatment planning, the clinical target volume (CTV) represents the tissue volume that contains demonstrable tumor and/or subclinical malignant disease that must be eliminated. This volume includes the gross tumor volume plus a margin for suspected microscopic extension. The CTV is determined by the radiation oncologist based on imaging studies, pathology findings, and knowledge of tumor biology and patterns of spread.
Usage
Usage note: Always capitalize when used as an acronym; lowercase when spelled out in running text.
In Context
- "The radiation oncologist contoured the clinical target volume to include a 5mm margin around the visible tumor." — Treatment planning document
- "Proper delineation of the CTV is critical for achieving local control while minimizing normal tissue toxicity." — Clinical protocol