Total Body Irradiation
Also written as: TBI — Total Body Irradiation
Radiation treatment technique delivering uniform dose to the entire body, typically used in bone marrow transplant conditioning regimens.
Full Definition
Total Body Irradiation (TBI) is a specialized radiation therapy technique that delivers a uniform radiation dose to the patient's entire body. This treatment is primarily used as part of conditioning regimens before bone marrow or stem cell transplantation to eliminate malignant cells and suppress the immune system. TBI requires extensive treatment planning to ensure dose uniformity across varied patient anatomy and specialized positioning techniques. The procedure involves strict quality assurance protocols and careful monitoring for acute and late toxicities including secondary malignancies.
Usage
Usage note: Commonly abbreviated as TBI in clinical documentation.
In Context
- "The total body irradiation protocol required lung shielding to reduce pneumonitis risk." — Treatment planning report
- "TBI dosimetry verification used multiple ionization chambers positioned across the patient's anatomy." — Physics quality assurance document