Skip to main content
Advanced Technical IVT

Locked-In Syndrome

A rare neurological condition characterized by complete paralysis except for eye movements, with preserved consciousness and cognitive function.

Full Definition

Locked-in syndrome is a rare neurological condition typically caused by damage to the brainstem, particularly the pons. Patients retain full consciousness and cognitive abilities but experience complete paralysis of voluntary muscles except for vertical eye movements and blinking. This creates a situation where patients are mentally alert but unable to speak or move their body. Communication is typically established through eye-coded systems or brain-computer interfaces. The condition presents unique challenges in rehabilitation settings, requiring specialized communication methods, extensive family education, and complex care coordination for long-term management.

Usage

Usage note: Often misdiagnosed initially as coma or vegetative state due to apparent unresponsiveness.

In Context

  • "The patient with locked-in syndrome communicated using vertical eye movements to indicate yes and no." — Nursing assessment
  • "Locked-in syndrome requires specialized communication training for both patient and family members." — Discharge planning

Also known as

cerebromedullospinal disconnection

Contrasted with

normal motor function

Don't confuse with

persistent vegetative state minimally conscious state coma

Editors from these organisations have used our services since 1998

Reuters BBC Oxford University Press Penguin Random House Springer Microsoft Suncor Energy United Nations Fisher Investments IBM The Home Depot KODAK CHEVRON