luteinized unruptured follicle syndrome

Full Definition

Luteinized unruptured follicle syndrome (LUFS) is a condition characterized by the apparent normal development and luteinization of the dominant follicle without actual ovulation occurring. The follicle continues to grow and produce hormones as if ovulation had occurred, leading to normal luteal phase hormone patterns despite the absence of actual ovulation. This condition can be a subtle cause of infertility, as it may be missed on routine hormone monitoring but can be detected through serial ultrasound examinations.

Usage

Usage note: Acronym LUFS is commonly used in clinical notes. Distinguished from simple anovulation by the presence of luteinization.

In Context

• "Serial ultrasounds revealed luteinized unruptured follicle syndrome as the cause of her unexplained infertility." — Diagnostic workup report
• "The patient's normal progesterone levels initially masked the underlying LUFS diagnosis." — Case study