Intermediate
Technical
IVT
aneuploid conceptus
Pronunciation: AN-you-ployd kon-SEP-tus
An embryo or fetus with an abnormal number of chromosomes.
Full Definition
An aneuploid conceptus refers to an embryo or fetus that possesses an abnormal chromosome number, deviating from the typical diploid count of 46 chromosomes. This includes conditions such as trisomies (extra chromosomes), monosomies (missing chromosomes), and higher-order aneuploidies. Aneuploid conceptuses are the most common cause of spontaneous abortion, with maternal age being a significant risk factor. In reproductive genetics, the detection and management of aneuploid conceptuses is central to prenatal screening and diagnosis protocols.
Usage
Usage note: Use 'conceptus' rather than 'fetus' when referring to early developmental stages.
In Context
- "The miscarriage tissue analysis revealed an aneuploid conceptus with trisomy 16." — Pathology report
- "Preimplantation genetic testing can identify aneuploid conceptuses before embryo transfer." — IVF laboratory protocol
Also known as
chromosomally abnormal embryo
Contrasted with
euploid conceptus
chromosomally normal embryo
Don't confuse with
polyploid conceptus
structurally abnormal embryo