Advanced
Technical
In the Industry Vocabulary Test
assisted hatching
Laboratory technique to create an opening in the embryo's protective shell to facilitate implantation.
Full Definition
Assisted hatching is an embryological procedure that involves creating a small opening or thinning in the zona pellucida surrounding an embryo before transfer. This technique can be performed mechanically, chemically, or with laser technology to help embryos that may have difficulty naturally hatching from their protective shell. The procedure is particularly considered for older patients, embryos with thick zona pellucida, or those that have been cryopreserved, as these factors may impede natural hatching and subsequent implantation.
Usage
Usage note: Indicates specific intervention distinct from natural embryo hatching process.
In Context
- "Laser-assisted hatching was performed on all embryos for this 42-year-old patient." — Embryology laboratory report
- "The decision to perform assisted hatching was based on the patient's advanced maternal age and previous implantation failure." — Treatment decision rationale
Also known as
zona drilling
zona breaching
Don't confuse with
zona pellucida drilling
embryo biopsy