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Intermediate Technical In the Industry Vocabulary Test

concordance

The degree to which genetic test results agree between different testing methods or between twins for a particular trait.

Full Definition

In reproductive genetics, concordance refers to the agreement or consistency of genetic findings, whether between different testing methodologies, between twins for inherited traits, or between test results and clinical phenotype. High concordance indicates reliable test results, while discordance may suggest testing limitations, mosaicism, or other genetic complexities. Concordance rates are critical metrics for evaluating the accuracy and reliability of genetic screening and diagnostic tests.

In Context

  • "The concordance between NIPT and invasive testing was 99.2% for trisomy 21 detection." — Clinical validation study
  • "Monozygotic twins showed 100% concordance for the identified genetic variant." — Genetic counseling report

Also known as

agreement consistency

Contrasted with

discordance disagreement

Don't confuse with

correlation penetrance

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