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In the Industry Vocabulary Test
controlled ovarian hyperstimulation
Hormonal treatment protocol to stimulate multiple follicle development for IVF cycles.
Full Definition
Controlled ovarian hyperstimulation (COH) is a pharmacological protocol using fertility medications to stimulate the ovaries to produce multiple mature follicles simultaneously, rather than the single follicle typical of natural cycles. The process involves gonadotropins, GnRH agonists or antagonists, and careful monitoring through ultrasound and hormone levels. This approach maximizes the number of oocytes available for retrieval while attempting to minimize complications like ovarian hyperstimulation syndrome.
Usage
Usage note: Often abbreviated as COH in clinical documentation.
In Context
- "The controlled ovarian hyperstimulation protocol was adjusted based on the patient's AMH levels and antral follicle count." — IVF treatment plan
- "Monitoring during controlled ovarian hyperstimulation revealed an excessive response requiring cycle cancellation." — Clinical progress notes
Also known as
COH
ovarian stimulation
superovulation
Contrasted with
natural cycle IVF
Don't confuse with
ovarian hyperstimulation syndrome
ovulation induction