embryo vitrification
Pronunciation: vit-rih-fih-KAY-shun
Ultra-rapid freezing technique for embryo cryopreservation that prevents ice crystal formation and maintains cellular integrity.
Full Definition
Embryo vitrification is an advanced cryopreservation technique that involves ultra-rapid cooling of embryos to cryogenic temperatures, creating a glass-like state without ice crystal formation. This method has largely replaced slower freezing protocols due to superior survival rates and maintained developmental potential. In reproductive genetics, vitrification is particularly important for preserving genetically tested embryos, allowing for frozen embryo transfer cycles after genetic analysis is complete. The technique requires precise timing and specialized equipment, but results in minimal cellular damage and high post-thaw survival rates. Vitrified embryos can be stored indefinitely while maintaining their genetic integrity.
Usage
Usage note: Often simply called 'freezing' in patient communication, though technically distinct.
In Context
- "All genetically normal embryos underwent vitrification pending results of the patient's medical clearance for transfer." — IVF cycle summary
- "The laboratory reported 100% survival rate for blastocysts after vitrification and warming procedures." — Quality assurance report