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recombination frequency
Percentage of offspring showing recombination between two genetic loci.
Full Definition
Recombination frequency measures the likelihood that crossing over will occur between two genetic loci during meiosis, expressed as a percentage. This parameter is crucial in reproductive genetics for linkage analysis, genetic mapping, and predicting inheritance patterns in families. A recombination frequency of 50% indicates independent assortment (unlinked loci), while frequencies less than 50% suggest genetic linkage. This information is particularly important in preimplantation genetic testing design and genetic counseling for linked disorders.
Usage
Usage note: Two words; not hyphenated.
In Context
- "The low recombination frequency between the markers made linkage analysis feasible." — Genetic analysis report
- "Recombination frequency data informed the family's reproductive decision-making." — Genetic counseling summary
Also known as
crossover frequency
Don't confuse with
mutation rate
allele frequency